The Clever Boys played out to a 1-1 draw at home in the first leg 10 days ago and needed an away goal to nullify the away goal rule which would see Enyimba advance.
Gavin Hunt’s men started well, Daine Klate with the first real effort at goal in the 22nd minute picked the ball up at the back post after a flicked header by Eleazar Rodgers but was unable to direct his effort at goal.
The People’s Elephants looked to play with pace on the counter and almost scored with their first attack of the game by Chinoso Okonkwo failed to hit the target with his effort.
Former Orlando Pirates goalkeeper Fatau Dauda did well to deny Ritchie five minuted before half time, punching out his rocket from range.
The sides went into the break locked at 0-0 with Wits most buoyed by the opening half.
Bongani Khumalo looked to have given Bidvest Wits the lead in the 55th minute, a glancing header at the front post that seemed destined for the back of the net was kept out by Dauda with a great reflex save.
Edwin Gyimah received his marching orders in the 68th minute after a challenge on Austin Oladapo saw him pick up a straight red card.
With the game coming to it’s conclusion, Wits had a chance to seal their spot in the next round when Rodgers and Mncwango broke away but were unable to capitalise on the two-on-one situation.
The hosts won a penalty in added time after Omofoman was brought down in the area. Kyle Peters doing well to deny Oladapo from the spot, the rebounded effort crashing into the side-netting.
The result brings to an end Wits’ involvement in the 2018 edition of the CAF Confed Cup, but the club optimistic about future tournaments and the learnings taken from this year.